|
Symbol Name ID |
Mlh1
mutL homolog 1 MGI:101938 |
| Darker colors indicate more annotations |
| Human Phenotypes | Ovarian neoplasm |
Endometrial carcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with MLH1 | |||
| colorectal cancer | |||
| Lynch syndrome | |||
| Muir-Torre syndrome |
| Mouse Phenotypes | azoospermia |
oligozoospermia |
abnormal chiasmata formation |
abnormal female meiosis |
abnormal male meiosis |
arrest of male meiosis |
abnormal meiotic spindle morphology |
decreased corpora lutea number |
abnormal ovarian folliculogenesis |
small ovary |
small testis |
increased uterus tumor incidence |
female infertility |
male infertility |
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| Availability | Mouse Genotype | ||||||||||||||
| Mlh1tm1b(EUCOMM)Hmgu/Mlh1tm1b(EUCOMM)Hmgu | |||||||||||||||
| Mlh1tm1Lisk/Mlh1tm1Lisk | |||||||||||||||
| Mlh1tm1Rak/Mlh1tm1Rak | |||||||||||||||
| Mlh1tm1Wed/Mlh1tm1Wed | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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